Choroidal thickness in acute and convalescent VKH disease

Abstract

SummaryVogt‐Koyanagi‐Harada (VKH) disease is a systemic autoimmune disorder against melanocytes, and is one of the leading causes of uveitis in many countries including Japan. The distribution of the melanocytes in the systemic organ such as eyes, internal ears, meninges, or skin, leads to the various symptoms or signs of VKH disease. Because melanocytes are abundantly present in the choroid, the primary site of the intraocular inflammation of VKH disease is the choroid. Therefore, to monitor the disease activity of VKH disease, indocyanine green angiography (ICGA) had long been the most useful tool. Recently, advances in optical coherence tomography (OCT) made it possible to visualize the cross section of the choroid in addition to the retina, and the findings in choroidal OCT are found to complement those in ICGA. In this presentation, the features of the choroidal changes by ICGA and OCT in VKH disease are discussed.