Abstract
Choroidal neovascularisation (CNV) is a rare but serious complication of Best disease. However, visualisation of the neovascular membrane is difficult on fluorescein angiography (FA) and indocyanine green angiography (ICGA) due to dye leakage from material accumulation. The authors' study reports a case series of paediatric Best's disease where optical coherence tomography angiography (OCT‐A) contributed to the diagnosis of CNV and prompt treatment.Three eyes of three patients with Best's disease were included. The mean age at diagnosis was 5.6 years (range 4‐7 years). OCT‐A showed the typical sea fan‐shaped neovascular membrane in three eyes, whereas in most cases conventional FA and ICGA imaging did not clearly show neovascularisation due to the masking effect of vitelliform material. OCT‐A appears to be a good alternative for diagnosing CNV in Best's disease, particularly in children, as it is a non‐invasive and rapid imaging technique that does not require the administration of dyes.The aim was to evaluate the effect of intravitreal injections on choroidal neovascularisation in patients with Best's disease using OCT and OCT‐A and to assess the increase in visual acuity after rehabilitation. During the talk, a literature data review on pathogenesis, evolution and future perspectives will be presented.
Published Version
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