Abstract

BackgroundThe global Choosing Wisely campaign has identified the following psychotropic prescribing as low-value (harmful or wasteful): (1) benzodiazepine use in the elderly, (2) antipsychotic use in dementia and (3) prescribing two or more antipsychotics concurrently. We aimed to quantify the extent of these prescribing practices in the Australian population.MethodsWe applied indicators to dispensing claims of a 10% random sample of Australian Pharmaceutical Benefits Scheme beneficiaries to quantify annual rates of each low-value practice from 2013 to 2016. We also assessed patient factors and direct medicine costs (extrapolated to the entire Australian population) associated with each practice in 2016.ResultsWe observed little change in the rates of the three practices between 2013 and 2016. In 2016, 15.3% of people aged ≥65 years were prescribed a benzodiazepine, 0.5% were prescribed antipsychotics in the context of dementia and 0.2% of people aged ≥18 years received two or more antipsychotics concurrently. The likelihood of elderly people receiving benzodiazepines or antipsychotics in the context of dementia increased with age and the likelihood of receiving all three practices increased with comorbidity burden. In 2016, direct medicine costs to the government of all three practices combined, extrapolated to national figures, were > $21 million AUD.ConclusionsOur indicators suggest that the frequency of these three practices has not changed appreciably in recent years and that they incur significant costs. Worryingly, people with the greatest risk of harm from these prescribing practices are often the most likely to receive them.

Highlights

  • The global Choosing Wisely campaign has identified the following psychotropic prescribing as low-value: (1) benzodiazepine use in the elderly, (2) antipsychotic use in dementia and (3) prescribing two or more antipsychotics concurrently

  • Medicines of interest We included medicines belonging to Anatomical Therapeutic Chemical Classification (ATC) classes antipsychotics (NO5A), benzodiazepines (NO5BA, NO5CD and NO3AE) and anti-dementia medicines (NO6D) [9] that were Pharmaceutical Benefits Scheme (PBS)-subsidised in Australia during the study period

  • According to our indicators, we found little to no change in the annual rates of each low-value prescribing practice across the study years

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Summary

Introduction

The global Choosing Wisely campaign has identified the following psychotropic prescribing as low-value (harmful or wasteful): (1) benzodiazepine use in the elderly, (2) antipsychotic use in dementia and (3) prescribing two or more antipsychotics concurrently. The conception of the global Choosing Wisely campaign has heralded a renewed interest in addressing low-value care; medical practices such as test ordering, procedures or prescribing that are either harmful or wasteful [1]. The majority of previous population-based research on low-value care has focused on medical tests and procedures [5], with limited attention to low-value prescribing practices [6]. This is despite the fact that when the nominated low-value practices in each country participating in the Choosing Wisely campaign are pooled, prescribing. Within the constraints of data content, individuallevel analyses enhance measurement approaches by allowing individuals receiving low-value prescribing practices to be more accurately identified

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