Chondroid lipoma: A rare recently described benign lipomatous tumor

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Introduction: lipomatous tumors group is a group of tumors containing both benign and malignant neoplasm, that sometimes have some morphological overlapping. chondroid lipoma is one of the rare benign lipomatous tumors that have been described recently. Although it is benign in nature, its microscopic picture is mimicking some of the malignant tumors, especially myxoid liposarcoma. case report: A 51-year-old female presented with a mass arising on her right thigh. this mass grew slowly during the several months ago. radiologically, it was described as a well-circumscribed benign mass with scanty fatty component. surgical excision and primary closure was performed for the patient. Histopathological examination demonstrated a well-circumscribed mass formed by cords and nests of lipoblasts and lipocytes embedded in a prominent myxoid to hyalinized chondroid matrix. A panel of immunohistochemical (IHc) stains had been done. From the clinical, radiological, and pathological information, the diagnosis of chondroid lipoma was made. conclusion: this case is considered a rare variant of lipoma and easily can be misdiagnosed as myxoid liposarcoma or extra-skeletal myxoid chondrosarcoma. so, the pathologist should be