Abstract
This study investigated the correlation of firing pattern of the cholinergic neurons in the brainstem and the fluctuation of blood pressure during paradoxical sleep (PS) in unanesthesized, head-restrained rats. Of 13 cholinergic neurons recorded from the laterodorsal tegmental nucleus, five showed phasic firing, which was in close correlation with the fluctuation of the blood pressure during PS. The increase in firing was observed 1–3s prior to the increase of blood pressure. The results suggest that a population of cholinergic neurons in the brainstem are closely involved in the fluctuation of blood pressure during PS.
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