Abstract

In brain tissue there are two pathways by which choline and ethanolamine can be incorporated into a lipid-bound form. The first is the cytidine pathway originally described by Kennedy and Weiss (1956) for liver and the second, though it is probably a minor pathway, is a calciummediated exchange where the base is exchanged with that of an intact phospholipid (Ansell & Spanner, 1966; Porcellati, et al., 1971; Kanfer, 1972). In this account the first step of the cytidine pathway will be discussed in detail and in particular, this step in the nerve endings of brain.

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