Abstract
Lung surfactant (LS) is a lipid-protein mixture that forms a monolayer that lines the alveolar air-liquid interface and acts to reduce the interfacial tension to a level necessary for breathing. The lack or inhibition of LS can be life threatening and can result in acute respiratory distress syndrome (ARDS) which has a 40% mortality rate. Due to the complexity of native LS, 2 or 3 component mixtures are studied to elucidate the relationship between composition, monolayer microstructure, and phase behavior and how these factors affect physiological function.
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