Abstract
The interaction of copaiba oil in the polymer matrix of chitosan can produce a favorable synergistic effect and potentiate properties. Indeed, the bioactive principles present in copaiba oil have anti-inflammatory and healing action. In the present work, chitosan membranes containing different contents of copaiba oil copaíba (0.1, 0.5, 1.0 and 5.0% (v/v)) were for the first time investigated. The membranes were developed by the casting method and analyzed for their morphology, degree of intumescence, moisture content, contact angle, Scanning Electron Microscope, and X-ray diffractometry. These chitosan/copaiba oil porous membranes disclosed fluid absorption capacity, hydrophilic surface, and moisture. In addition, the results showed that chitosan membranes with the addition of 1.0% (v/v) of copaiba oil presented oil drops with larger diameters, around 123.78 μm. The highest fluid absorption indexes were observed in chitosan membranes containing 0.1 and 0.5% (v/v) of copaiba oil. In addition, the copaiba oil modified the crystalline structure of chitosan. Such characteristics are expected to favor wound treatment. However, biological studies are necessary for the safe use of chitosan/copaiba oil membrane as a biomaterial.
Highlights
Academic Editors: Shubham Sharma, Jujhar Singh, Rushdan Ahmad Ilyas, Mavinkere Rangappa Sanjay and Engineering of Natural Resources of the Amazon Program, Federal University of Pará—UFPA, Rua Augusto
The present results showed that the membranes were able to promote fluid absorption
The diffractions of 2 broad peaks in 2θ: 10.55, 23.373, 2θ: 11.55, and 23.70, respecPolymeric membranes composed of chitosan and copaiba oil were successfully detively, were analyzed
Summary
Academic Editors: Shubham Sharma, Jujhar Singh, Rushdan Ahmad Ilyas, Mavinkere Rangappa Sanjay and Engineering of Natural Resources of the Amazon Program, Federal University of Pará—UFPA, Rua Augusto. It is necessary that the dressing is nonallergenic, non-toxic, maintains moisture, allows gas exchanges, protects the wound against pathogenic microorganisms, and absorbs exudates from the wound. It must stimulate growth factors, promote tissue granulation and reepithelization, and be easy to remove [1,2]. In addition to these attributes, researchers are currently searching for dressing covers that interact with the wound and release natural bioactive molecules that provide elements necessary for wound healing [3]. Chitosan is a natural cationic biopolymer [6] and has been considered in various biomedical applications, including wound healing, because of its many biological and physical-chemical published maps and institutional affiliations
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