Abstract

Chicken essence (CE) is a liquid nutritional supplement made from cooking whole chickens. In traditional Chinese medicine, CE is used to support health, promote healing, increase metabolism, and relieve fatigue. However, few studies have examined the effect of CE on exercise performance and physical fatigue. We aimed to evaluate the potential beneficial effects of CE on fatigue and ergogenic functions following physical challenge in mice. Male ICR mice were divided into four groups to receive vehicle or CE by oral gavage at 0, 845, 1690, or 4225 mg/kg/day for 4 weeks. Exercise performance and anti-fatigue function were evaluated by forelimb grip strength, exhaustive swimming time, and levels of physical fatigue-related biomarkers serum lactate, ammonia, glucose, and creatine kinase (CK) after physical challenge. CE supplementation dose-dependently elevated endurance and grip strength. CE supplementation significantly decreased lactate, ammonia, and CK levels after physical challenge. Tissue glycogen content, an important energy source for exercise, was significantly increased with CE supplementation. In addition, CE supplementation had few subchronic toxic effects. The supplementation with CE can have a wide spectrum of bioactivities on health promotion, performance improvement and anti-fatigue.

Highlights

  • In traditional Chinese medicine, chicken essence (CE) is a liquid nutritional supplement made from cooking whole chickens

  • Absolute grip strength was lower for vehicle- than Chicken essence (CE)-treated groups

  • Previous study has shown a positive correlation between grip strength and anthropometric factors such as age, weight, body mass index and waist circumference [17]

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Summary

Introduction

In traditional Chinese medicine, chicken essence (CE) is a liquid nutritional supplement made from cooking whole chickens. It is used for strengthening the bones and muscles, invigorating the spleen and stomach, and enhancing vigor. As compared with other kinds of meat, chicken contains higher protein and is richer in trace elements, amino acids, carnosine, and creatinine, and these ingredients can be extracted into broth or soup. CE differs in ingredient proportions and bioactivities from chicken broth because the processing involves high-temperature extraction, centrifugation, vacuum concentration, and sterilization. CE contains some special nutrients such as carnosine and anserine, taurine, vitamins, minerals, trace elements, and indispensable amino acids [1]. In previous reports related to physiological functions, CE exhibited bioactivities of anti-stress or anti-mental fatigue via cortisol regulation [2] and activation of the central histaminergic system [3]

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