Chicken cerebrospinal fluid: Insulin-like activity

Abstract

1. 1. 14C-inulin passage across the avian blood-brain barrier was facilitated by beef insulin. 2. 2. Insulin-like activity of normal chicken cerebrospinal fluid was determined by the rat diaphragm method and equated to beef insulin standards. 3. 3. Intravenous insulin did not alter cerebrospinal fluid-insulin-like activity levels; tolbutamide increased the insulin-like activity 5 min after injection and possibly again 60 min later.