Abstract
Aims: To examine the chemistry of two California Lycium species and evaluate the possible use of California Lycium species as dietary supplements especially for age related macular degeneration.
 Study Design: This exploratory analytical research used samples of Lycium andersonii and Lycium cooperi collected in the field and analyzed in the lab.
 Place and Duration of Study: University of Southern California School of Pharmacy, 1985 Zonal Avenue, Los Angeles, CA USA 90089.
 Methodology: Plant extracts were analyzed by high pressure liquid chromatography mass spectrometry with ultraviolet photodiode array detection in order to identify the chemical characteristics of compounds found in the plants.
 Results: Several known compounds were found in extracts of Lycium cooperi and Lycium andersonii foliage and fruit including: zeaxanthin, zeaxanthin monopalmitate and β-cryptoxanthin. The various California species of Lycium are discussed as possible alternatives to Chinese Lycium barbarum.
 Conclusion: California Lycium berries may be suitable substitutes for Chinese Lycium berries.
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