ChemInform Abstract: Statistical Study of the Influence of the Nitro Groups on the Ionization and Solvation Processes of Disubstituted Benzoic Derivatives

Abstract

Abstract The influence of nitro groups on the ionization and solvation processes of disubstituted benzoic derivatives was studied from the statistical viewpoint. This study was carried out by considering the enthalpy values of these processes to be a linear combination of the enthalpy values of the same processes in the corresponding mononitrosubstituted compounds. A range of mole fractions (0-0.8) of water-DMSO mixtures was used. Diparametric and monoparametric regression analyses were carried out. In these analyses, total standard deviations, slope and intercept standard deviations, correlation coefficients, Student t -tests and F-tests of the above values were taken into account. Particular attention was paid to the presence of the collinearity between the explanatory variables. The introduction of a nitro group in position 4 both for the 3,4- and 2,4-dinitro derivatives is the dominant factor of the corresponding ionization processes.