Abstract
AbstractDie N‐Propargyl‐benzoylglutaminsäureester (I) werden mit dem Brommethylchinazolin (II) zu den N‐Propargyl‐5,8‐dideazafolsäuren (III) umgesetzt, die auf Inhibierung der L1210‐Thymidylat‐Synthase und der Dihydrofolat‐Synthase sowie auf Inhibierung des Wachstums von L12lO‐Zellen geprüft werden.
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