ChemInform Abstract: Functionalization of (2S)‐Isopropyl‐5‐iodo‐2,3‐dihydro‐4(H)‐pyrimidin‐4‐ones by a Suzuki—Miyaura Cross‐Coupling Reaction Using Aryltrifluoroborate Salts: Convenient Enantioselective Preparation of α‐Substituted β‐Amino Acids.

Abstract

AbstractA large variety of groups present in the potassium aryltrifluoroborates (‐CF3, ‐OMe, ‐SEt, ‐CN, ‐CHO, ‐Cl, ‐Cbz, ‐OH) are tolerated in the title reaction.