ChemInform Abstract: Formation of Contiguous Quaternary and Tertiary Stereocenters by Sequential Asymmetric Conjugate Addition of Grignard Reagents to 2‐Substituted Enones and Mg—Enolate Trapping.

Nicolas Germain, Alexandre Alexakis

https://doi.org/10.1002/chin.201541068

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Publication Date: Sep 24, 2015

Abstract

AbstractOptimized reaction conditions are developed for the asymmetric conjugate addition of Grignard reagents to α‐substituted cyclic enones.

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