Abstract
The first reports of the application of commercial microwave ovens to the synthesis of small organic molecules appeared in 1986 [1, 2]. Microwave irradiation proved then to be extremely useful for promoting and simplifying of many condensation reactions which can be carried both in the solvent and solvent-free conditions [3—7]. The classical Perkin reaction of the cinnamic acids consists of prolonged (8—10 h) heating of the benzaldehyde, the acetic anhydride, and a catalyst to 180◦C [8—13]. We describe herein the attempts to perform efficient Perkin reaction in the microwave oven. The goal of this work was to examine the catalyst effect and to study the influence of the substituents on the course and yields of this reaction.
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