Abstract
Abstract An enantioselective reduction and acetylation of esters to α-acetoxy ethers is described. Reduction with a NaAlH 4 –ephedrine reagent followed by in situ acetylation gives 2 with good enantiomeric excess. This reaction is limited in scope, but it demonstrates that enantioselective reductions of esters are possible.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have