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https://doi.org/10.1002/chin.201640203
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Cite Journal: ChemInform |  Publication Date: Sep 1, 2016 |
Affiliation: Soonchunhyang University
Chiral binaphthyl-modified squaramide-catalyzed enantioselective addition of diphenyl phosphonate to ketimines derived from isatins has been achieved. This method affords practical and efficient access to chiral 3-amino-3-phosphonyl-substituted oxindole derivatives in high yields with excellent enantioselectivities (up to 99% ee).
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