ChemInform Abstract: Direct Regiospecific and Highly Enantioselective Intermolecular α‐Allylic Alkylation of Aldehydes by a Combination of Transition‐Metal and Chiral Amine Catalysts.

Abstract

AbstractThe present allylic alkylation of various linear aldehydes (II), catalyzed by an achiral palladium complex and a chiral amine as co‐catalyst, gives the corresponding alcohols after in situ reduction with NaBH4.