ChemInform Abstract: Cobalt‐Catalyzed Enantioselective Hydrogenation of Minimally Functionalized Alkenes: Isotopic Labeling Provides Insight into the Origin of Stereoselectivity and Alkene Insertion Preferences.

Max R Friedfeld,Paul J Chirik,Louis-Charles Campeau,Michael Shevlin,Grant W Margulieux

doi:10.1002/chin.201634040

ChemInform Abstract: Cobalt‐Catalyzed Enantioselective Hydrogenation of Minimally Functionalized Alkenes: Isotopic Labeling Provides Insight into the Origin of Stereoselectivity and Alkene Insertion Preferences.

Max R Friedfeld, Paul J Chirik + Show 3 more

https://doi.org/10.1002/chin.201634040

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Journal: ChemInform

Publication Date: Aug 1, 2016

Affiliation: Princeton University

#Origin Of Stereoselectivity #Isotopic Labeling #Insertion Preferences #Enantioselective Hydrogenation #Alkene Insertion #Active Compounds #Natural Products

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AbstractA highly enantioselective hydrogenation of cyclic and 1,1‐disubstituted alkenes, including substructures of natural products and biologically active compounds, is examined.

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ChemInform Abstract: Cobalt‐Catalyzed Enantioselective Hydrogenation of Minimally Functionalized Alkenes: Isotopic Labeling Provides Insight into the Origin of Stereoselectivity and Alkene Insertion Preferences.