ChemInform Abstract: Change of Regioselectivity in the Reaction of Tin Enolates and α-Bromo Ketones: Synthesis of 1,4-Diketones Under Non-Radical Conditions.

Abstract

The reaction of tin enolates with α-halogeno ketones, strikingly effected by the addition of phosphine oxides to the reaction mixture, produced 1,4-diketones under mild conditions; the addition was shown to proceed in a non-radical manner.