ChemInform Abstract: Catalytic Asymmetric Assembly of C3‐Monosubstituted Chiral Carbazolones and Concise Formal Synthesis of (‐)‐Aspidofractinine: Application of Enantioselective Pd‐Catalyzed Decarboxylative Protonation of Carbazolones.

Abstract

AbstractThe first catalytic enantioselective formal synthesis of (‐)‐aspidofractinine (II) is achieved via key intermediate (I), which is synthesized in only ten steps from commercially available starting materials.