ChemInform Abstract: C—H Bond Functionalization via Hydride Transfer: Formation of α‐Arylated Piperidines and 1,2,3,4‐Tetrahydroisoquinolines via Stereoselective Intramolecular Amination of Benzylic C—H Bonds.

Paul A Vadola,Dalibor Sames,Ignacio Carrera

doi:10.1002/chin.201251032

ChemInform Abstract: C—H Bond Functionalization via Hydride Transfer: Formation of α‐Arylated Piperidines and 1,2,3,4‐Tetrahydroisoquinolines via Stereoselective Intramolecular Amination of Benzylic C—H Bonds.

Paul A Vadola, Dalibor Sames + Show 1 more

https://doi.org/10.1002/chin.201251032

Copy DOI

Export

Save

Cite

Journal: ChemInform

Publication Date: Dec 10, 2012

Affiliation: Columbia University

#Presence Of BF3 #Hydride Transfer #Bond Functionalization #Stereoselective Intramolecular #Intramolecular Amination #Amination Of Benzylic

Abstract
Full-Text
Similar Papers

Abstract

Listen

AbstractTreatment of aldehydes of type (I), (IV), (VI), and (IX) with Tos‐NH2 leads to imines which in the presence of BF3·OEt2 undergo cyclization to α‐arylated piperidines and tetrahydroisoquinolines.

Full Text

Published Version

Check institute access

Open DOI Link

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Similar Papers

Paper Title

Journal

Date

Author

View more papers

More From: ChemInform

Paper Title

Journal

Date

Author

View more papers

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.

R Discovery Prime

ChemInform Abstract: C—H Bond Functionalization via Hydride Transfer: Formation of α‐Arylated Piperidines and 1,2,3,4‐Tetrahydroisoquinolines via Stereoselective Intramolecular Amination of Benzylic C—H Bonds.