ChemInform Abstract: Baylis—Hillman Acetates in Synthesis: Copper(I)/tert‐Butyl Hydroperoxide Promoted One‐Pot Oxidative Intramolecular Cyclization Protocol for the Preparation of Pyrrole‐Fused Compounds and the Formal Synthesis of (.+‐.)‐Crispine A.

Abstract

AbstractN‐Alkylation of tetrahydroisoquinolines or tryptoline with Baylis—Hillman acetates followed by intramolecular cyclization and oxdiative aromatization affords pyrrole‐fused compound including the precursor (VIII) of (.+‐.)‐crispine A.