ChemInform Abstract: Asymmetric Synthesis of β‐Trifluoromethyl‐β‐amino Acids, Including Highly Sterically Constrained α,α‐Dialkyl Derivatives.

Yanling Dai, Jianlin Han + Show 4 more

https://doi.org/10.1002/chin.201616070

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Publication Date: Mar 1, 2016

Abstract

AbstractTitle compounds are synthesized via Mannich addition reaction of chiral trifluoroacetaldimine and lithium enolates of alkyl acetates.

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