ChemInform Abstract: An Expedient Access to γ‐Ketophosphine Chalcogenides via the Chemo‐ and Regioselective Addition of Secondary Phosphine Chalcogenides to β,γ‐Ethylenic Ketones.

Abstract

γ-Ketophosphine chalcogenides, precursors for plethora of novel functionalized phosphine chalcogenides and phosphines, are synthesized by chemo- and regioselective addition of secondary phosphine chalcogenides to β,γ-ethylenic ketones under catalyst- and solvent-free conditions (80–100°C, 8–70 h) in excellent yields. The straightforward superbase-catalyzed synthesis of starting β,γ-ethylenic ketones from ketones and acetylenes insures the expedient access to the target γ-ketophosphine chalcogenides.