ChemInform Abstract: Aminobromination of β‐Nitrostyrene Derivatives with N,N‐Dibromourethane as the Aminobrominating Reagent.

Abstract

A concise and efficient aminobromination reaction for β-nitrostyrene derivatives by treatment with N,N-dibromourethane was developed. For the β-nitrostyrene derivatives, the aminobromination successfully proceeded at room temperature in CH3CN without catalysis or protection by an inert gas and gave products in excellent yields (80–97 %). For the β-methyl analogs, the reaction proceeded smoothly with anhydrous K2CO3 as a catalyst under the same conditions to provide the aminobrominated products in good yields (53–78 %). A possible pathway for this electrophilic addition reaction is proposed.