ChemInform Abstract: Alkylation of Imidazolidinone Dipeptide Derivatives: Preparation of Enantiomerically Pure Di‐ and Tripeptides by “Chirality Transfer” via a Pivalaldehyde N,N‐Acetal Center.

Abstract

AbstractGlycylglycine, (S)‐alanylglycine and glycyl‐(S)‐alanine esters are cyclized through the pivaldehyde imines (I), (IVa), and (IVb) to give the dipeptide‐derived imidazolidinones (III), (Va), and (VIb).