ChemInform Abstract: A Rapid and Efficient One‐Pot Method for the Reduction of N‐Protected α‐Amino Acids to Chiral α‐Amino Aldehydes Using CDI/DIBAL‐H.

Abstract

AbstractN‐Protected amino acids (I) and (III) are readily converted into the corresponding chiral aldehydes in a one‐pot reaction by activation with CDI followed by reduction with DIBAL‐H.