Abstract
Abstract An efficient L1 /Cu(II)-catalyzed highly chemoselective and enantioselective nitroaldol reaction of α- or β-haloenals with nitromethane has been described. The reaction delivered chiral functionalized allylic alcohols bearing halo and nitro groups with excellent results (up to 94% yield and 99% ee) under mild reaction conditions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have