Abstract
The protective effect of AET on mitotic activity and chromosome damage in intestinal crypt cells of X-irradiated mice has been studied. It was found that the number of chromosome fragments in the crypt cells of both treated and nontreated mice is dose dependent. In lethally X-irradiated mice given AET the number of chromosome fragments was less than that of nontreated mice; at supralethal X-ray doses, AET markedly protected mitotic activity. The data indicate that, in treated and nontreated mice, recovery of mitotic activity was inversely related to the number of chromosome fragments.
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