Abstract
Photochemical afterglow materials are gaining great attention for the property to continuously emit light after the excitation source is removed. However, their limited luminescence quantum yield(QY)and brightness hinder the use in biologicalapplications. In this study, we introduce a novel photochemical afterglow system that combines a newly designedphotoenergy cache unit (PCU) with an emitter throughcoordination covalent bonds. The PCU boastsa dark state to significantly emit photons onlythrough chemiexcitationin the process of photochemicalreactions, facilitating direct energy transfer to the emitter and resulting in bright afterglow. The related mechanisms further guided us to achieve thehighest reported afterglow luminescencequantum yieldof 27.5%. The systemcan be encapsulated and dispersed in aqueous solutions for in vivobioimaging inlivingmiceundermild and simple conditions(low concentration, low excitation power, short excitation time, short exposure time), and also forin vitrodiagnostic throughlateral flow immunoassay, enablingthe highly sensitive detection of the inflammatory biomarker serum amyloid A(SAA)anddemonstrating excellent correlation with clinical test results.This study offers new insights into enhancing luminescence QY and brightnessof afterglow, highlighting the potential of suchsystems for further biomedical applications.
Published Version
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