Abstract
From the methanol extract of the root of Streptocaulon juventas Merr, three cardenolide derivatives were isolated. Their strutures were determined by spectroscopic methods. This is the first time that (17α)-H-periplogenin-3-O-β-D-glucopyranosyl-(1–4)-2-O-acetyl-3-O-methyl-β- fucopyranoside (1) and periplogenin-3-O-β-cymaropyranosyl-(1®4)--glucopyranoside (2) were isolated from the root of S. juventas together with the known 17α-H-periplogenin-3-O-β- digitoxopyranosyl-(1®4)-O-β-glucopyranosyl-(1®6)-O-β-glucopyranoside (3).
Highlights
Their strutures were determined by spectroscopic methods
Bui Xuan Hao[1], Nguyen Minh Duc[2], Tran Le Quan[1] [1] University of Science, VNU HCM [2] Pharma Medical University of HCM city
Summary
Bùi Xuân Hào[1], Nguyễn Minh ðức[2], Trần Lê Quan[1] [1]Trường ðại Học Khoa Học Tự Nhiên, ðHQG-HCM [2] Trường ðại Học Y Dược Tp. HCM TÓM TẮT: Từ dịch chiết metanol của rễ cây hà thủ ô trắng, ba hợp chất khung cardenolid ñã ñược cô lập, trong ñó 17α-H-periplogenin-3-O-β-D-glucopyranosyl-(1–4)-2-O-acetyl-3-O-methyl-βfucopyranoside và periplogenin-3-O-β-cymaropyranosyl-(1→4)-β-glucopyranoside là các hợp chất lần ñầu tiên ñược tìm thấy trong rễ cây hà thủ ô trắng. Ngoài ra một dẫn xuất cardenolid ñã biết là 17α-Hperiplogenin-3-O-β-digitoxopyranosyl-(1→4)-O-β-glucopyranosyl-(1→6)-O-β-glucopyranoside cũng ñược cô lập. Cấu trúc các hợp chất này ñược làm sáng tỏ bằng các phương pháp phổ nghiệm
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