Abstract
Strains of Salmonella typhimurium which are unable to synthesize their own iron transport agents and require an erogenous chelator were used to examine extracts of the wood of species of Cupressaceae for the presence of iron chelators. Wood from 19 species of five genera were examined and all were found to contain substances that would function as iron transport agents for S. typhimurium. The biological activity of most of these species could be explained by the known presence and activity of the thujaplicins. Juniperus virginiana and J. occidentalis were found to contain a non-tropolone substance that functioned as chelators in S. typhimurium. The tropolone nootkatin from Chamaecyparis nootkatensis was ineffective as an iron transport agent.
Published Version
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