Abstract
A simple and sensitive spectrophotometric method employing acid-dye technique was developed for the estimation of etoricoxib in pharmaceutical dosage form. The proposed method is based on the formation of ion-pair complex of etoricoxib with an acid dye, which is extracted into chloroform and the absorbance measured at the λmax of the complex. The λmax of the ion-pair complex was found to be 414nm. Beer’s law was obeyed in the concentration range of 10-80 µg/ml .The proposed method is statistically validated and found to be useful for the routine determination of etoricoxib in tablets. Keywords: Etoricoxib, Spectrophotometry, Charge transfer complex, Tablets, Validation.
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