Abstract

The complete genome sequence of beak and feather disease virus (BFDV) from a wild Australian Mallee ringneck parrot (Barnardius zonarius barnardi) was characterized. The genome consists of 1,995 nucleotides and encodes two major proteins in opposing directions. This is the first evidence of BFDV infectivity and the first complete genome sequence for this novel host.

Highlights

  • The complete genome sequence of beak and feather disease virus (BFDV) from a wild Australian Mallee ringneck parrot (Barnardius zonarius barnardi) was characterized

  • The disease is caused by one of the smallest and simplest viruses belonging to the family Circoviridae, beak and feather disease virus (BFDV), a nonenveloped icosahedral virus with an approximately 2.0-kb circular single-stranded DNA genome

  • We characterize the complete BFDV genome isolated from a wild Mallee ringneck parrot (Barnardius zonarius barnardi) in Australia

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Summary

Introduction

The complete genome sequence of beak and feather disease virus (BFDV) from a wild Australian Mallee ringneck parrot (Barnardius zonarius barnardi) was characterized. Psittacine beak and feather disease (PBFD) is a common viral infection that occurs in a wide variety of psittacine birds, globally affecting Ͼ60 different species [1,2,3,4]. The genome typically encompasses two major bidirectionally transcribed open reading frames (ORFs) encoding replication-associated protein (Rep) and capsid protein (Cap), with a potential stem-loop structure located between them [5,6,7].

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