Abstract
We confirmed the specific detection of immunoglobulin E (IgE) using an aptamer-immobilized reduced graphene oxide (rGO) field effect transistor (FET). The detection limit and dynamic range were estimated to be 8.1 ng/ml and 104, respectively. These characteristics are comparable with these of current fluorescent markers. Although the mobility of rGO-FET was around 6 cm2 V−1 s−1, which is two to three orders lower than that of mechanically exfoliated pristine graphene FET, its sensitivity to IgE was only one order lower than that of pristine graphene FET.
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