Abstract
Aim Confocal Endomicroscopy (CEM) is a non invasive imaging tool enabling optical biopsies of tissues at cellular level. Clinical studies have successfully reported the accuracy of CEM for the characterization of gastrointestinal, dermatologic and ocular diseases. In this study, we assess the potential use of endomicroscopy in combination with fluorophores clinically approved, to characterize premalignant and malignant lesions in human larynx.
Highlights
1S1.pdcientific Meeting of the Head and Neck Optical Diagnostics Society Colin Hopper, Adel K El-Naggar, Tahwinder Upile, Waseem Jerjes and HJCM Sterenborg Publication of this supplement was made possible with support from KARL STORZ Endoskope Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/
Our results demonstrated the promising use of fluorescence endomicroscopy for discriminating cancerous and non cancerous region in larynx
A homogeneous and regular nuclear distribution was showed in squamous epithelium with both Confocal Endomicroscopy (CEM) and confocal imaging
Summary
Muriel Abbaci*1, Stephane Temam, Odile Casiraghi, Philippe Vielh, Jacques Bosq, Pierre Fouret and Corinne Laplace-Builhé. Address: 1Cell imaging and Flow cytometry, Institut Gustave Roussy, Villejuif, France, 2Department of Otorhinolaryngology and Head and Neck Surgery, Institut Gustave Roussy, Villejuif, France and 3Department of Pathology, Institut Gustave Roussy, Villejuif, France. Published: 28 July 2009 Head & Neck Oncology 2009, 1(Suppl 1):O14 doi:10.1186/1758-3284-1-S1-O14. 1S1.pdcientific Meeting of the Head and Neck Optical Diagnostics Society Colin Hopper, Adel K El-Naggar, Tahwinder Upile, Waseem Jerjes and HJCM Sterenborg Publication of this supplement was made possible with support from KARL STORZ Endoskope Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/
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