Characterization, development and evaluation of a cream by using terminalia chebula and cucumber sativus extracts

Abstract

Background: Continual exposure to the sun's ultraviolet radiation damages skin. Freckles are little brown patches that develop on the skin after repeated sun exposure. Terminalia chebula and Cucumber Sativus extracts-infused water in oil (W/O) emulsion is created, that has anti-freckle and emollient effect. Methodology: Base with no extract and formulation containing three different extract concentrations 4% of Terminalia Chebula with 1% Cucumber Sativus, 5% T. Chebula with 2% C. Sativus and 6% of T. Chebula with 3% of C. Sativus are formulated and after 4 weeks of study and their stability parameters are evaluated at 8oC, 25oC, 40oC and 40oC + 75RH. Different parameters such as anti freckle effect, skin melanin, skin moisture content, sebum level and TEW loss level are investigated by applying these formulations on the volunteer’s cheeks for 4 weeks. Results: Skin melanin levels, sebum level, moisture level and TEW loss level of three formulations containing both plant extracts are significant statistically (p < 0.05). Skin melanin level and TEW loss are decreased after application of cream. But skin moisture and sebum level are increased after application of formulation.