Characterization, anticancer, antibacterial, anti-diabetic and anti-inflammatory activities of green synthesized silver nanoparticles using Justica wynaadensis leaves extract

Abstract

In this experiment plant mediated method used to prepare silver nanoparticles using Justica wynaadensis leaf extract. The leaf extract solution reduced and stabilized the AgNO3 into Silver nanoparticles. The synthesis of silver nanoparticles was observed by the colour reaction and monitored by UV–visible spectroscopy in the range of 400 nm to 500 nm for silver nanoparticles. The synthesized nanoparticles were subjected to characterization technique by using X-ray diffraction (XRD), Transmission Electron Microscope (TEM), Fourier Transform Infrared spectroscopy (FTIR). TEM analysis of the silver nanoparticles were found to be crystalline in structure, varying in size from 30 nm to 50 nm. The biological activities of Ag nanoparticles showed significant results against anti-bacterial, anticancer activity (Cell line A549). The anti-diabetic and anti-inflammatory activities of Justica wynaadensis Ag nanoparticles also has proved that it is a good alternatives in medicine and industrial application.