Characteristics of HPV infection in women at risk in Western Algeria

Abstract

ObjectivesWe aimed to characterize HPV infections and cervical lesions in Western Algeria. Patients and methodsA total of 96 cervical samples obtained from women at risk of HPV infection (HIV-1-infected or presenting with a gynecological disease) were analyzed to characterize this infection and search for cytological abnormalities. ResultsA total of 60% of women at risk had an HPV infection. The rate of high-risk HPV (HR-HPV) infection among these women was 84.5% and that of intraepithelial lesions was 29.3%. The frequency of HPV infection was significantly higher among HIV-1-infected patients. An association between the presence of HR-HPV and the polygamy of the partner was observed. An association between cytological abnormalities and the use of oral contraceptives was observed among HIV-1-infected women. ConclusionGiven the high frequency of HPV infection in this at risk population, close monitoring and regular gynecological screening are essential.