Character of Phospholipid (Acetone Insoluble) Fatty Acids of Serum in Infantile Eczema.

Abstract

Summary and ConclusionsIn a study of the serum lipids of 7 infants with severe, generalized eczema by a microgravimetric method, the phospholipid (acetone insoluble) fatty acids were found to be more unsaturated and to have higher average molecular weights than the total fatty acids. When these findings were compared with similar information obtained in a previous study on fourteen essentially normal infants and children, the degree of unsaturation of both the total fatty acids and the phospholipid fatty acids was found to be definitely less in the eczematous subjects. These data confirm a previous finding of the author that the iodine numbers of the serum lipids tend to be lower in infants with severe eczema. In addition, they reveal the fact that the fatty acids in the phospholipid (acetone insoluble) fraction of the serum lipids partake in this reduction.