Abstract
The Clostridia do not grow under ordinary aerobic conditions, but some, such as Cl. welchii and Cl. sporogenes, multiply under micro-aerophilic conditions. The spores of the Clostridia are resistant to the ordinary bactericidal agents. Tetanus is a disease of antiquity and is widely distributed throughout the world. Its incidence is low considering the great possibility of infection with Cl. tetani, which has been isolated with frequency from soil and the feces of man and animals. Gas gangrene, a common disease in the days of pre-antiseptic surgery, is a rarity in civil practice. The anaerobes not infrequently give rise to wound infection and might also be responsible for cases of puerperal fever and mild types of enteritis, but the classical cases of gas gangrene are seldom seen. Botulism in man is a rare disease, which follows the ingestion of contaminated food, such as sausages, prepared meats, canned foods, vegetables, and fish. Botulism is essentially a toxaemia and not an infection. The symptoms are caused by a preformed toxin ingested with food and absorbed from the alimentary tract.
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