Abstract
This chapter presents the approaches to the understanding of senescence. There are many different ways of attempting a scientific approach to the problem of senescence. The chapter discusses the evolutionary-genetic approach and environmental considerations. To discover an elixir of life would be socially disastrous. Perhaps fortunately, there seems to be no approach by which one might tamper with the genetic program that define, barring untimely accident, how long one shall live. Any attempt to change the order of nature, to provide, for example basic good health to the age of 90, would have to intervene at some point in the processes that eventually give phenotypic expression to the genetic program for length of life. It is still not firmly established that thymic function and immunological processes generally have any influence on the intrinsic ageing process; however, effective they may be in handling accidental hazards to life such as infection and neoplasia.
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