Abstract
Abstract With increasingly effective medical interventions for congenital heart disease and leukemia, more individuals with Down syndrome (DS) are living into adulthood and old age. To enable children and adults with DS to be healthy and able to function well and live life fully, we need to be knowledgeable about the plethora of medical problems that are possible. In individuals with DS, each system has the potential of some or several types of medical problems that may require constant surveillance such as celiac disease or monitoring such as thyroid disease. These disorders may be more prevalent at different ages, such as arthropathy of DS, or constantly a potential issue, such as atlantoaxial subluxation. This chapter describes by system the multitude of potential medical problems that individuals with DS have an increased chance of developing at different ages.
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