Abstract

In this chapter, an overview of surface modification of biomaterials is given from the standpoint of general concepts and the application of such concepts to the treatment of bone disorders and diseases. Concepts include the use of current biomedical devices for treatment of bone fractures and the need for coating technologies that can augment implant surfaces for improved physiological performance. Methods of characterization and in vitro analysis are described as well. Properties of surface modification including surface tension and surface chemical coordination are discussed as they pertain to the formation of biomineralized tissues. Surface modifications of biomaterials for the fabrication of biosensors are also discussed as they could have potential use as “on-board” sensors for cancerous lesions. Future directions are presented as well to illustrate the need for future biomaterial development using surface modification.

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