Abstract
This chapter aims to classify context-specific subjects as either treatment responders or nonresponders to antidepressant medication. The method used includes the Intelligent Treatment Management System (ITMS). The ITMS performs electroencephalography (EEG)-based prediction of treatment outcomes of antidepressant therapy (ITMS-treatment selection), while classifying major depressive disorder (MDD) patients as either treatment respondents (R) or nonrespondents (NR) based on pretreatment EEG data acquired from MDD patients. The EEG-based scheme presented in this chapter inherently involves subprocesses such as noise removal from EEG data, EEG-based feature extraction, feature selection, classification, and validation, including 10-fold cross-validation (10-CV). This chapter provides technical details regarding these subprocesses.
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