Abstract
Experiments revealed that aqueous suspensions of saturated monoglycerides (with acyl chain lengths over 10 carbons) combined with cholesterol and cholesterol derivatives readily formed concentrated gas-in-water emulsions when shaken vigorously (in an air atmosphere). Using laser-based flow cytometry and forward-angle light scattering (detection limit = 0.3 µm), the calculated concentration of synthetic microbubbles in the filtered sample is approximately 7 × 105 microbubbles/ml. Further measurements also indicated that very slow dissolution of the newly formed, surfactant-coated microbubbles does continue for a period. Moreover, this gradual rate of dissolution of the artificial microbubbles can apparently be increased somewhat by circulating the liquid.
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