Abstract
In this chapter, we summarize all the studies carried out on CDCA1, the first member of the ζ-class of carbonic anhydrase family. CDCA1 turned out to be a highly versatile enzyme, being able to use for the catalysis of two different metal ions, such as Zn2+ and Cd2+, and to catalyze two different reactions, namely the CO2 hydration and the conversion of CS2 to H2S. These properties are discussed in detail and interpreted in light of the capacity of diatoms, which express CDCA1-like proteins, to survive in limiting conditions.
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