Abstract
Reproductive endocrinology describes the hormones and control mechanisms that regulate sexual development, sexual function, and reproduction. Disorders of reproductive endocrinology can occur from abnormal changes anywhere in the hypothalamus–pituitary–gonadal axis and can include a wide range of symptoms including infertility, hirsutism, virilization, oligomenorrhea and amenorrhea in women, and infertility and altered sexual function in men. This chapter describes the approach to diagnosis and evaluation of disorders of the reproductive endocrinology system. Considerations and challenges in laboratory testing for reproductive hormones, including assay interferences, standardization, and differences between immunoassay and mass spectrometry methods, will also be discussed.
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